Production of teicoplanin from Actinoplanes teichomyceticus ID9303 by adding proline.
نویسندگان
چکیده
We evaluated the influence of amino acids in improving teicoplanin productivity. Arginine, lysine, and proline were selected for better productivity among 20 amino acids in Erlenmeyer flasks. Proline was finally chosen as the additive for maximum teicoplanin productivity in a 5-liter fermenter. We obtained the highest teicoplanin productivity, 3.12 g/l, on the eighth d in a 75-liter pilot fermenter.
منابع مشابه
Actinoplanes teichomyceticus ATCC 31121 as a cell factory for producing teicoplanin
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عنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 72 6 شماره
صفحات -
تاریخ انتشار 2008